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At normal doses, it should not affect any routine blood tests.
Ibuprofen belongs to a class of drugs called non-steroidal anti-inflammatory drugs, or NSAIDs, which includes aspirin too. It is a non-selective inhibitor of cyclo-oxygenase (COX), inhibiting both COX-1 and COX-2. That enzyme is responsible for producing one of the molecules that is involved in inflammation. It also can inhibit the function of platelets, which are a component of blood that participate in coagulation, so it may alter coagulation testing. This effect is temporary, unlike aspirin, which permanently inhibits platelet function for the lifetime of the platelets, which is about a week.
It will not affect platelet count, and neither does aspirin…the effect of low-dose aspirin is to modify the way platelets work in forming clots, not decreasing their numbers. However, ibuprofen may interfere with that effect of aspirin.
Its just a pain reliver and doesnt stay in your system and routine blood work doesnt look for any drugs just for say liver functions or check blood cells
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I know that ibuprofen works by thinning your blood, which decreases vascular pressure and inflammation.
Ibuprofen taken just before a routine blood test might show a lower platelet count…platelets determine bleeding times.
But unless you take it 3–4 times a day for months or years, it shouldn’t affect the blood test. Be sure to let the lab tech know so they can make a note of it on your test result.
I agree with the other answers. I would add only a small bit of info related to drug kinetics. The half-life of ibuprofen is 2.1 hours. Half the drug is out of your system in that time. In 4.2 hours 75% is gone. In 6.3 hours 87.5% is gone (and so on). You have no effective amount of the medication for about 18 hours of the day, assuming you are taking 2 tablets at once of the over-the-counter strength (200 mg x 2 = 400 mg). So you are taking a (1) small amount of (2) a low dose that (3) doesn’t last very long having (4) minimal daily effect. Your liver does not significantly process ibuprofen, but your kidneys do. And for most of the 24 hour clock they’ll be unaffected based on the drug behavior described above.
My stage 4 kidney cancer was detected because my blood calcium level was too high. This was an indication of a cancer somewhere. It could have been a cancer in my bones releasing calcium from them, but in my case, most of 1 kidney was cancerous, so the kidneys were unable to remove as much calcium as usual from the blood they were filtering. A CT scan showed where the cancer was.
Two things here:
- My GP made a very good pick up to spot the high calcium level and get it checked with a CT scan. All the specialists I have since seen have said so, suggesting many doctors would have thought ‘let’s wait and see what it is next time’. There would have been NO next time – if they hadn’t done the operation then to take out the kidney, I was literally weeks (not months) from death. You bet I gave my GP a big hug!
- Unfortunately, this symptom only occurred when the cancer was so advanced and serious. I was having blood tests every 3 months so we knew it had not been high 3 months prior. So you cannot rely on a blood test for early detection of this sort of cancer. My surgeon said this tumour had been growing for decades.
In short, I was lucky … and I still am 3.5 years later!
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Yes it does. Ibuprofen works like aspirin. I can bore you with the details, but it does multiple things in your body.
Specific to thinning your blood – Ibuprofen blocks two cyclooxygenase (COX) enzymes, one of which converts a certain prostaglandin to thromboxane-a2. This chemical is involved in platelet aggregation (clotting).
Basically it prevents them from getting sticky.
If your platelets can’t clot, then your blood is “thinner”.
I made an assumption that everyone knows that aspirin thins your blood but if you didn’t know, well it does. It does it in the same way. The only difference is when aspirin binds the COX receptor it is irreversible where as Ibuprofen is not.
Ibuprofen will thin your blood for about 6 to 8 hours max. Aspirin will do it until you make new platelets. That should take 3 days to replace the ones you blocked completely.
Ibuprofen belongs to a class of medications called “non-steroidal anti-inflammatory drugs,” or NSAIDs (pronounced “enn-sehds”).
NSAIDs are inhibitors of an enzyme called cyclooxygenase, or COX, which is an important enzyme related to inflammation and your immune system.
There’s different versions of COX, but you don’t need to worry about that. The important thing to remember, is that COX is involved in synthesizing compounds called “prostaglandins” and “thromboxanes.” These compounds mainly act as inflammatory mediators, but they also influence several other important functions within the body.
Prostaglandins, in particular, are involved with relaxing smooth muscle and causing blood vessels to dilate, which means that they increase their diameter. The larger the diameter of a blood vessel is, the lower the blood pressure in that vessel will be.
So, more prostaglandins=lower blood pressure. Easy, right?
Give an NSAID, that means less COX. Less COX = less prostaglandins and thromboxanes.
Less prostaglandins = less dilation of arteries = higher blood pressure.
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The human body is a marvelous thing. If you eat, then various molecular switches and processes are enacted and hydrogen ions (H+) are pumped out into the lumen of the stomach (the space inside) and loosely combine with chloride ions (Cl-) to form an environment of hydrochloride acid (HCl) inside the stomach largely to break apart proteins (and kills lots of microorganisms as another benefit). The stomach lining produces a mucous that protects the stomach from the acid.
All this is interesting, but the system only turns on when food is introduced that requires digestion. If you don’t eat, your stomach produces very little acid. Sometimes it is producing none at all. All the while, the mucous secretions keep up with whatever need arises from general wearing away of the coating or the stomach producing a little bit of acid. It is well-balanced and is not easily fooled by a person skipping meals or drinking only water. Your body is more finely-tuned than that to be so easily fooled.
Now, smell a kitchen full of wonderfully deliciously aromatic foods and your salivary glands will start secreting (mouth watering) and a little acid will be produced by the stomach—along with the mucous secretions that protect the stomach—in anticipation of eating. But, if you fail to eat any of that food, the acid secretions soon cease.
So, the simplest answer to your question is:
No, if you don’t eat (skip a meal or even fast several days) your stomach does not continue to produce mealtime levels of acid. The mucous secretions continue to protect the stomach lining. The only way this changes is if you have a particular illness or have a serious infection in the stomach of some particular microorganisms (Helicobacter pylori being the most well known bacterium that infects the stomach lining).
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